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THE CONSORTIUM

 

The TEMPO consortium comprises 11 partner institutions from five European countries including three small and medium size enterprise (SME).

Coordinator is Inserm, the French National Institute of Health and Medical Research
TEMPO was launched in October 2006 and will run for a period of three years.
The consortium is a highly multi-disciplinary network integrating competencies in molecular biology, modelling, pharmacokinetics, pharmacodynamics, cancer application.

 
INSERM

Team « Rythmes biologiques et cancers », INSERM, Villejuif (France)

Francis Lévi - Scientific Coordinator

rbc_logo”Rythmes Biologiques et Cancers” laboratory has been conducting basic and clinical research on the relevance of bodily clocks for human health at Paul Brousse hospital, Villejuif (France) since 1981. Most of the research activities have focused on the implications of the circadian timing system for cancer progression and treatments. 
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CNRS

Team «Biologie et physiopathologie des systèmes intégrés », CNRS, Sophia Antipolis (France)

Franck Delaunay

The Nice Sophia Antipolis University was founded in 1965 and is now the second largest multidisciplinary University in France with 25 000 students. The life science department includes 24 laboratories with a majority being joint laboratories with Centre National de la Recherche Scientifique, Institut National de Santé et de Recherche Médicale and Institut National de la Recherche Agronomique. A total of 270 scientists, 200 ingeniors and technicians as well as 200 phD students and postdocs are currently working in these laboratories. Main research areas include molecular pharmacology, animal and plant physiology, development, signalling and cancer.

 

Team «Molécules et cibles thérapeutiques », CNRS, Roscoff (France)

Laurent Meijer

The team is located in the Station Biologique at Roscoff in Brittany. It possesses all equipment required to search for, optimize and characterize pharmacological inhibitors of protein kinases including a screening robot. it has also all the expertise, experience and equipment to analyze the cellular effects of kinase inhibitors. It has access to a biosafety level 2 cell culture laboratory.

 

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INRIA

Team «BANG : Nonlinear Analysis for Biology and Geophysical flows», INRIA, Roquencourt,  (France)

Jean Clairambault

INRIA, the national institute for research in computer science and control, operating under the dual authority of the Ministry of Research and the Ministry of Industry, is dedicated to fundamental and applied research in information and communication science and technology (ICST). The Institute also plays a major role in technology transfer by fostering training through research, diffusion of scientific and technical information, development, as well as providing expert advice and participating in international programs. By playing a leading role in the scientific community in the field and being in close contact with industry, INRIA is a major participant in the development of ICST in France.

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CINBO

« Gabriele d'Annunzio » University , CINBO, Chieti, (Italy)

Stefano Iacobelli 

The group has a long standing experience in production and purification of human and rodent recombinant proteins. Moreover, the group has experience in the production of monoclonal and polyclonal antibodies and in the development of antibody-based assays for the determination of protein content in complex mixtures. Available facilities and resources The group has access to state-of-the-art facilities and equipments at the Center of Excellence on Aging, “G. D’Annunzio” Foundation, Chieti, including: DNA array and proteomic analysis, yeast two hybrid screening and TAP-tag affinity chromatography/nanospray mass spectrometry, pathogen-free animal laboratory.

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HOSPITAL SERVICES

HS Hospital Service and  Department of Oncolog, SCarlo Borromeo Hospital (Milan), HS, Aprilia (Italy)

Marco Pirovano

HS Hospital Service , who develops and market medical devices for minimal invasive medical procedures.
We work in close collaboration with the San Carlo Borromeo Hospital Oncology Depth., the Famacology Department of Milan University School of Medicine.
Our group has a long standing experience in clinical oncology, pharmacology, molecular biology finalized to technology transfer. The group has large experience in clinical trials in colon-rectal cancer and Chronotherapy, genotype-phenotype relationship in pharmacokinetics, development and production of biomedical technology.

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HELIOS BIOSCIENCES
Helios BioSciences,HELIOS, Paris (France)
 
Todor Vujasinovic

Helios BioSciences, a French company incorporated in 2002, characterizes new drug targets to treat diseases in which the physiological death and/or survival of specific cells are impaired: cancer, neurodegenerative diseases and diseases of immunity.
To do this, Helios has developed and validated a proprietary software platform for dynamic systems biology.
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PHYSIOMICS

Physiomics plc, Oxford (UK)

Christophe Chassagnole

Physiomics, an Oxford based company, was founded in 2001 and AIM listed in December 2004 on the London Stock exchange. Physiomics develops computational systems biology models to predict and understand cancer drug efficacy from pre-clinical research to clinical development. Physiomics has created a detailed mathematical model incorporating most important molecular events taking place during the human cell cycle. Physiomics developed SystemCell(r), a multi-cellular environment software, which enables the simulation of population of "virtual cells".

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INSERM TRANSFERT

Inserm Transfert, Paris (France)

Isabelle Geahel - Project Manager

INSERM-Transfert, a subsidiary of INSERM (1), is a public limited company that possesses extensive expertise in two core areas. Technology transfer and the funding and creation of biotechnology enterprises represent one of the core expertises. The second core expertise is dedicated project management activities.

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